Peer Reviewed Research Papers

  • Clearance of an amyloid-like translational repressor is governed by 14-3-3 proteins.Herod SG, Dyatel A, Hodapp S, Jovanovic M, Berchowitz LE. Cell Reports. 2022. May 3;39(5):110753.

  • Pal I, Grilo AS, Gaspary A, Sharma SD, Scotto L, O'Connor OA, Jovanovic M, Changchun D, Berchowitz LE. Inhibition of Casein Kinase 1 Delta Disrupts Translation Initiation and Exerts Potent Anti-Lymphoma Activity. Blood Advances. 2022 May 25

  • Identification of 14-3-3 proteins, Polo kinase, and RNA-binding protein Pes4 as key regulators of meiotic commitment in budding yeast. Gavade JN, Puccia CM, Herod SG, Trinidad JC, Berchowitz LE, & Lacefield S. Current Biology. 2022. 32(7), 1534-1547

  • The cAMP signaling pathway regulates heterochromatin assembly. Bao K, Shan C-M, Chen X, Raiymbek G, Munroe J, Koutmou K, Ragunathan K, Lu C, Berchowitz LE, and Jia S. PLoS Genetics. 2022. 18(2)

  • Meiotic cells counteract programmed retrotransposon activation via RNA-binding translational repressor assemblies. Laureau R, Dyatel A, Dursuk G, Brown S, Adeoye H, Yue J-X, De Chiara M, Harris A, Ünal E, Liti G, Adams IR, Berchowitz LE. Developmental Cell. 2021. 56(1), 22-35

  • Fusobacterium nucleatum secretes amyloid-like FadA to enhance pathogenicity. Meng Q, Gao Q, Mehrazarin S, Tangwanichgapong K, Wang Y, Huang Y, Pan Y, Robinson S, Liu Z, Zangiabadi A, Lux R, Papapanou PN, Guo XE, Wang H, Berchowitz LE*, Han YW*. EMBO Reports. 2021. e52891. *co-corresponding

  • Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability. Bryant EE, Sunjevaric I, Berchowitz LE, Rothstein RR and Reid RJD. Nucleic Acids Research. 2019. 47(17), 9144-9159

  • Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis. Sawyer EM, Joshi PR, Jorgensen V, Yunus J, Berchowitz LE, & Ünal E. Journal of Cell Biology. 2019. 218(2): 559-579

  • Granules bearing translation factor mRNAs direct the protein synthetic machinery to regions of polarized growth. Pizzinga M, Bates C, Lui J, Forte G, Linney E, Morales F, Knotkova B, Wilson B, Solari CA, Berchowitz LE, Portela P, Ashe, MP. Journal of Cell Biology. 2019. 218(5), 1564-1581

  • Carptenter K, Bell RB, Yunus J, Amon A, Berchowitz LE. Phosphorylation-Mediated Clearance of Amyloid-like Assemblies in Meiosis. Developmental Cell. 2018. 45(3). p392–405

  • Phizicky DV, Berchowitz LE, Bell SP. Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis. eLife. 2018. Feb 1;7:e33309.

  • Berchowitz, LE, Kabachinski G, Walker MR, Carlile TM, Gilbert WV, Schwartz TU, Amon A. Regulated formation of an amyloid-like translational repressor governs gametogenesis. Cell. 2015. 163(2). 406-418

  • Ziolkowski PA, Berchowitz LE, Lambing C, Yelina NE, Zhao X, Kelly KA, Choi K, Ziolkowska L, June V, Sanchez-Moran E, Franklin C, Copenhaver GP, Henderson IR. Juxtaposition of heterozygosity and homozygosity during meiosis causes reciprocal crossover remodeling via interference. eLife. 2015. 10.7554/eLife.03708

  • Berchowitz LE, Gajadhar A, van Werven FJ, De Rosa AA, Samoylova ML, Brar GA, Xu Y, Xiao C, Futcher B, Weissman JS, White F, Amon A. A developmentally-regulated translational control pathway establishes the meiotic chromosome segregation pattern. Genes and Development. 2013. 27(19): 2147-2163

  • Sun Y, Ambrose JH, Haughey BS, Webster TD, Pierrie SN, Muñoz DF, Wellman EC, Cherian S, Lewis SM, Berchowitz LE, Copenhaver, GP. Deep Genome-Wide Measurement of Meiotic Gene Conversion Using Tetrad Analysis in Arabidopsis thaliana. PLoS Genetics. 2012. 8(10): e1002968.

  • d'Erfurth, I., Cromer, L., Jolivet, S., Girard, C., Horlow, C., Sun, Y., To, J. Berchowitz, LE, Copenhaver, GP, Mercier, R.The cyclin-A CYCA1; 2/TAM is required for the meiosis I to meiosis II transition and cooperates with OSD1 for the prophase to first meiotic division transition. PLoS Genetics. 2010. 6(6)

  • Berchowitz LE*, Hanlon SE*, Lieb JD, Copenhaver GP. A positive but complex association between meiotic double-strand break hotspots and open chromatin in Saccharomyces cerevisiae. Genome Research. 2009. Dec 19(12): 2245-57. *equal contribution

  • Berchowitz LE, Copenhaver GP. Fluorescent Arabidopsis tetrads: A visual assay for quickly developing large crossover and crossover interference datasets. Nature Protocols. 2008. 3(1): 41-50*.

  • Berchowitz LE, Francis KE, Bey AL, Copenhaver GP. The Role of AtMUS81 in Interference-Insensitive Crossovers in A. thaliana. PLoS Genetics. 2007. 3: e132.

  • Francis KE, Lam SY, Harrison BD, Bey AL, Berchowitz LE, Copenhaver GP. Pollen Tetrad-based Visual Assay for Meiotic Recombination in Arabidopsis. Proceedings of the National Academy of Sciences. 2007. 104: 3913-3918.

 Editorial and Review

  •  The role of disorder in RNA binding affinity and specificity. Ottoz DSM, and Berchowitz LE. Open Biology. 10.12. 2020. 200328

  • Induced pluripotent stem cells as a tool for comparative physiology: lessons from the thirteen-lined ground squirrel. Ou J, Rosa S, Berchowitz LE, Li, W. Journal of Experimental Biology. 2019. 222 (19), jeb196493

  • Berchowitz LE, Copenhaver GP. Genetic Interference: Don’t Stand So Close To Me. Current Genomics. 2010. 11: 91-102.

  • Berchowitz LE, Copenhaver GP. Visual markers for detecting gene conversion directly in the gametes of Arabidopsis thaliana. Methods in Molecular Biology. 2009. 557:99-114.

  • Berchowitz LE and Copenhaver GP. Division of Labor Among Meiotic Genes.  Nature Genetics. 2008. 40:266-267.